SV 2

Highly glycosylated synaptic vesicle protein with homology to transmembrane transporters

References SySy SV 2 antibodies

Lazarevic V, Schöne C, Heine M, Gundelfinger ED & Fejtova A (2011). Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing. Journal of Neuroscience 31: 10189-200. SV 2B rabbit antibody; WB, ICC

Boido D, Farisello P, Cesca F, Ferrea E, Valtorta F, Benfenati F & Baldelli P (2010). Cortico-hippocampal hyperexcitability in synapsin I/II/III knockout mice: age-dependency and response to the antiepileptic drug levetiracetam. Neuroscience 171: 268-83. SV 2A, SV 2B, SV 2C rabbit antibodies; WB

Lee H & Brecha NC (2010). Immunocytochemical evidence for SNARE protein-dependent transmitter release from guinea pig horizontal cells. European Journal of Neuroscience 31: 1388-1401. SV 2A rabbit antibody; IHC

Grønborg M, Pavlos NJ, Brunk I, Chua JJ, Münster-Wandowski A, Riedel D, Ahnert-Hilger G, Urlaub H & Jahn R (2010). Quantitative comparison of glutamatergic and GABAergic synaptic vesicles unveils selectivity for few proteins including MAL2, a novel synaptic vesicle protein. Journal of Neuroscience 30: 2-12. SV 2C; WB, ICC, IHC

van Vliet EA, Aronica E, Redeker S, Boer K & Gorter JA (2009). Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy. Epilepsia 50: 422-33. SV 2A rabbit antibody; WB, IHC on paraffin-embedded tissue

Rummel A, Häfner K, Mahrhold S, Darashchonak N, Holt M, Jahn R, Beermann S, Karnath T, Bigalke H Binz T (2009). Botulinum Neurotoxins C, E and F Bind Gangliosides via a Conserved Binding Site Prior to Stimulation Dependent Uptake with Botulinum Neurotoxin F Utilising the Three Isoforms of SV2 as Second Receptor. Journal of Neurochemistry 110: 1942-54. SV 2C; WB

Couesnon A, Pereira Y & Popoff MR (2008). Receptor-mediated transcytosis of botulinum neurotoxin A through intestinal cell monolayers. Cellular Microbiology 10: 375-87. SV 2A and B rabbit antibodies; WB

Miyauchi N, Saito A, Karasawa T, Harita Y, Suzuki K, Koike H, Han GD, Shimizu F & Kawachi H (2006). Synaptic vesicle protein 2B is expressed in podocyte, and its expression is altered in proteinuric glomeruli. Journal of the American Society of Nephrology 17: 2748-59. SV 2B rabbit antibody; WB, ICC, IHC

Schivell AE, Mochida S, Kensel-Hammes P, Custer KL, Bajjalieh SM (2005). SV2A and SV2C contain a unique synaptotagmin-binding site. Molecular and Cellular Neurosciences 29: 56-64. SV 2B rabbit antibody; WB

Iwata N, Mizukami H, Shirotani K, Takaki Y, Muramatsu SI, Lu B. Gerard NP, Gerard C, Ozawa K & Saido TC (2004). Presynaptic localization of neprilysin contributes to efficient clearance of amyloid - peptide in mouse brain. Journal of Neuroscience 24: 991-8. SV 2A rabbit antibody; IHC

Xu T, von Kriegstein K & Schmitz F (2003). The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell Tissue Research 311: 159-73.

von Kriegstein K & Schmitz F (2003). The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell and Tissue Research 311: 159-73. SV 2A and B rabbit antibodies; IHC

Redecker P, Kreutz MR, Bockmann J, Gundelfinger ED & Boeckers TM (2003). Brain synaptic junctional proteins at the acrosome of rat testicular germ cells. Journal of Histochemistry and Cytochemistry 51: 809-19. SV 2B rabbit antibody; WB, IHC

von Kriegstein K, Schmitz F, Link E & Sudhof T (1999). Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. European Journal of Neuroscience 11: 1335-48.

Janz R & Sudhof TC (1999). SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family. Neuroscience 94: 1279-90. SV 2A and B rabbit antibodies; WB, IHC

General references SV 2

Xu T & Bajjalieh SM (2001). SV2 modulates the size of the readily releasable pool of secretory vesicles. Nature Cell Biology. 3: 691-8.

Fernandez-Chacon R & Sudhof TC (1999). Genetics of synaptic vesicle function: toward the complete functional anatomy of an organelle. Annual Review of Physiology 61: 753-76. Review

Südhof TC (1995). The synaptic vesicle cycle: a cascade of protein - protein interactions. Nature 375: 645-53. Review

Bajjalieh SM, Frantz GD, Weimann JM, McConnell SK & Scheller RH (1994). Differential expression of synaptic vesicle protein 2 (SV2) isoforms. Journal of Neuroscience 14: 5223-35.

Jahn R & Südhof TC (1994). Synaptic vesicles and exocytosis. Annual Review of Neuroscience 17: 219-46. Review, no abstract available

Bajjalieh SM, Peterson K, Shinghal R & Scheller RH (1992). SV2, a brain synaptic vesicle protein homologous to bacterial transporters. Science 257: 1271-3.

Feany MB, Lee S, Edwards RH & Buckley KM (1992). The synaptic vesicle protein SV2 is a novel type of transmembrane transporter. Cell 70: 861-7.