SNAP 47

A novel member of the Qbc SNARE family

General Information

The membrane bound protein SNAP 47 is abundantly expressed in different tissues. The highest protein levels have been observed in brain. Like its closest relative SNAP 29 it lacks a membrane anchor and the mechanism which mediates the membrane localization is still under investigation.
SNAP 47 co-purifies with synaptic vesicles but shows a staining pattern different from typical synaptic vesicle markers like synapsin or synaptophysin.
SNAP 47 may be localized to a vesicle-pool which has not been confined to a special organelle but accumulates in the periphery of the trans-Golgi-network.