SNAP 25

Palmitoylated plasma membrane protein; required for exocytosis

References SySy SNAP 25 antibodies

Mendez JA, Bourque MJ, Fasano C, Kortleven C & Trudeau LE (2011). Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels. Journal of Biological Chemistry May 16. [Epub ahead of print] rabbit antibody; ICC

Smith R, Klein P, Koc-Schmitz Y, Waldvogel HJ, Faull RL, Brundin P, Plomann M & Li JY (2007). Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. Journal of Neurochemistry 103: 115-23. IHC

Breen LT, Smyth LM, Yamboliev IA & Mutafova-Yambolieva VN (2005). β-NAD is a novel nucleotide released on stimulation of nerve terminals in human urinary bladder detrusor muscle. American Journal of Physiology. Renal Physiology 290: F486-95. WB

Eberhorn AC, Horn AK, Eberhorn N, Fischer P, Boergen KP & Büttner-Ennever JA (2005). Palisade endings in extraocular eye muscles revealed by SNAP-25 immunoreactivity. Journal of Anatomy 206: 307-15. IHC

Reim K, Wegmeyer H, Brandstätter JH, Xue M, Rosenmund C, Dresbach T, Hofmann K& Brose N (2005). Structurally and functionally unique complexins at retinal ribbon synapses. Journal of Cell Biology 169: 669-80. Clone 71.1; WB

Nagy G, Reim K, Matti U, Brose N, Binz T, Rettig J, Neher E & Sørensen JB (2004). Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25. Neuron 41: 351-65. Clone 71.1; WB

Reisinger C, Yelamanchili SV, Hinz B, Mitter D, Becher A, Bigalke H & Ahnert-Hilger G (2004). The synaptophysin/synaptobrevin complex dissociates independently of neuroexocytosis. Journal of Neurochemistry 90: 1-8.

Wojcik SM, Rhee JS, Herzog E, Sigler A, Jahn R, Takamori S, Brose N & Rosenmund C (2004). An essential role for vesicular glutamate transporter1 (VGLUT1) in postnatal development and control of quantal size. Proceedings of the National Academy of Sciences USA 101: 7158-63. WB

von Kriegstein K& Schmitz F (2003). The expression pattern and assembly profile of synaptic membrane proteins in ribbon synapses of the developing mouse retina. Cell Tissue Research 311: 159-73. Clone 71.2; IHC

Varoqueaux F, Sigler A, Rhee JS, Brose N, Enk C, Reim K & Rosenmund C (2002). Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proceedings of the National Academy of Sciences USA 99: 9037-42. WB

Lang T, Margittai M, Holzler H & Jahn R (2002). SNAREs in native plasma membranes are active and readily form core complexes with endogenous and exogenous SNAREs. Journal of Cell Biology 158: 751-60.

von Kriegstein K, Schmitz F, Link E & Sudhof T (1999). Distribution of synaptic vesicle proteins in the mammalian retina identifies obligatory and facultative components of ribbon synapses. European Journal of Neuroscience 11: 1335-48.

Xu T, Rammner B, Margittai M, Artalejo AR, Neher E & Jahn R (1999). Inhibition of SNARE complex assembly differentially affects kinetic components of exocytosis. Cell 99: 713-22. Epitope mapping of clones 71.1 and 71.2

Bruns D, Engers S, Yang C, Ossig R, Jeromin A & Jahn R (1997). Inhibition of transmitter release correlates with the proteolytic activity of tetanus toxin and botulinus toxin A in individual cultured synapses of Hirudo medicinalis. Journal of Neuroscience 17: 1898-910. Description of clone 71.1

General references SNAP 25

Lin RC & Scheller RH (2000). Mechanisms of synaptic vesicle exocytosis. Annual Reviews of Cell and Developmental Biology 16: 19-49. Review

Jahn R & Südhof TC (1999). Membrane fusion and exocytosis. Annual Review of Biochemistry 68: 863-911. Review

Fasshauer D, Bruns D, Shen B, Jahn R & Brunger AT (1997). A structural change occurs upon binding of syntaxin to SNAP-25. Journal of Biological Chemistry 272: 4582-90.

Südhof TC (1995). The synaptic vesicle cycle: a cascade of protein - protein interactions. Nature 375: 645-53. Review

Schulze KL, Broadie K, Perin MS and Bellen HJ (1995). Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission. Cell 80: 311-20.

Jahn R & Südhof TC (1994). Synaptic vesicles and exocytosis. Annual Review of Neuroscience 17: 219-46. Review, no abstract available

Blasi J, Chapman ER, Link E, Binz T, Yamasaki S, De Camilli P, Sudhof TC, Niemann H & Jahn R (1993). Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25. Nature 365: 160-3.