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SY SY - Synaptic Systems SY SY - Synaptic Systems

Shank 1

A multidomain protein of the postsynaptic density

General references shank 1

Sala C, Roussignol G, Meldolesi J & Fagni L (2005). Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons. Journal of Neuroscience 25: 4587-92.

Roussignol G, Ango F, Romorini S, Tu JC, Sala C, Worley PF, Bockaert J & Fagni L (2005). Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons. Journal of Neuroscience 25: 3560-70.

Quitsch A, Berhorster K, Liew CW, Richter D & Kreienkamp HJ (2005). Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180. Journal of Neuroscience 25: 479-87.

Qualmann B, Boeckers TM, Jeromin M, Gundelfinger ED & Kessels MM (2004). Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. Journal of Neuroscience 24: 2481-95. Erratum in: Journal of Neuroscience 24: following 3849.

Im YJ, Lee JH, Park SH, Park SJ, Rho SH, Kang GB, Kim E & Eom SH (2003). Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization. Journal of Biological Chemistry 278: 48099-104.

Boeckers TM, Bockmann J, Kreutz MR & Gundelfinger ED (2002). ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease. Journal of Neurochemistry 81: 903-10. Review

Sala C, Piech V, Wilson NR, Passafaro M, Liu G & Sheng M (2001). Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31: 115-30.

Tobaben S, Sudhof TC & Stahl B (2000). The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. Journal of Biological Chemistry 275: 36204-10.

Sheng M & Kim E (2000). The Shank family of scaffold proteins. Journal of Cell Science 113 (Pt 11): 1851-6. Review

Naisbitt S, Kim E, Tu JC, Xiao B, Sala C, Valtschanoff J, Weinberg RJ, Worley PF & Sheng M (1999). Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron 23: 569-82.


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Synaptic Systems GmbH | Rudolf-Wissell-Str. 28 | 37079 Göttingen | Germany
Phone: +49 (0)551/505 56-0 | Internet: http://www.sysy.com | E-Mail: sales@sysy.com