SF3a 120

A member of the U2 snRNP

General Information

In eukaryotic cells introns are removed from pre-mRNAs by the splicesome which consists of the U1, U2, U4, U5 and U6 small nuclear ribonucleoprotein particles (snRNPs) and other proteins.
The splicing factor SF3a is a member of the U2 snRNP. It is composed of three subunits (60 kDa, 66 kDa and 120 kDa) and has been shown to be essential for the assembly of functional 17S U2 snRNP in vitro.