Synaptopodin

An actin associated protein present in renal podocytes and telencephalic dendrites

References SySy synaptopodin antibodies

Chen S, Wassenhove-McCarthy D, Yamaguchi Y, Holzman L, van Kuppevelt TH, Orr AW, Funk S, Woods A & McCarthy K (2011). Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices. Kidney International 78: 1088-99. rabbit antibody; IHC

Cohen JW, Louneva N, Han LY, Hodes G, Wilson RS, Bennett DA, Lucki I & Arnold SE (2010). Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain. Synapse 65: 763-70. rabbit antibody; WB, IHC

Tarabra E, Giunti S, Barutta F, Salvidio G, Burt D, Deferrari G, Gambino R, Vergola D, Pinach S, Perin PC, Camussi G & Gruden G (2009). Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes 58: 2109-18. rabbit antibody; IHC

Vlachos A, Korkotian E, Schonfeld E, Copanaki E, Deller T & Segal M (2009). Synaptopodin regulates plasticity of dendritic spines in hippocampal neurons. Journal of Neuroscience 29: 1017-33. rabbit antibody; WB, ICC

General references synaptopodin

Verpoorten N, Verhoeven K, Weckx S, Jacobs A, Serneels S, Del Favero J, Ceuterick C, Van Bockstaele DR, Berneman ZN, Van den Bosch L, Robberecht W, Nobbio L, Schenone A, Dessaud E, deLapeyriere O, Huylebroeck D, Zwijsen A, De Jonghe P & Timmerman V (2005). Synaptopodin and 4 novel genes identified in primary sensory neurons. Molecular and Celluar Neurosciences 30: 316-25.

Czarnecki K, Haas CA, Bas Orth C, Deller T & Frotscher M (2005). Postnatal development of synaptopodin expression in the rodent hippocampus. Journal of Comparative Neurology 490: 133-44.

Bas Orth C, Vlachos A, Del Turco D, Burbach GJ, Haas CA, Mundel P, Feng G, Frotscher M & Deller T (2005). Lamina-specific distribution of Synaptopodin, an actin-associated molecule essential for the spine apparatus, in identified principal cell dendrites of the mouse hippocampus. Journal of Comparative Neurology 487: 227-39.

Asanuma K, Kim K, Oh J, Giardino L, Chabanis S, Faul C, Reiser J & Mundel P (2005). Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific manner. Journal of Clinical Investigation 115: 1188-98.

Kremerskothen J, Plaas C, Kindler S, Frotscher M & Barnekow A (2005). Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding protein. Journal of Neurochemistry 92: 597-606.

Deller T, Korte M, Chabanis S, Drakew A, Schwegler H, Stefani GG, Zuniga A, Schwarz K, Bonhoeffer T, Zeller R, Frotscher M & Mundel P (2003). Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity. Proceedings of the National Academy of Sciences USA 100: 10494-9.

Yamazaki M, Matsuo R, Fukazawa Y, Ozawa F & Inokuchi K (2001). Regulated expression of an actin-associated protein, synaptopodin, during long-term potentiation. Journal of Neurochemistry 79: 192-9.

Roth SU, Sommer C, Mundel P & Kiessling M (2001). Expression of synaptopodin, an actin-associated protein, in the rat hippocampus after limbic epilepsy. Brain Pathology 11: 169-81.

Deller T, Mundel P & Frotscher M (2000). Potential role of synaptopodin in spine motility by coupling actin to the spine apparatus. Hippocampus 10: 569-81. Review

Deller T, Merten T, Roth SU, Mundel P & Frotscher M (2000). Actin-associated protein synaptopodin in the rat hippocampal formation: localization in the spine neck and close association with the spine apparatus of principal neurons. Journal of Comparative Neurology 418: 164-81.

Mundel P (1998). Synaptopodin: an actin-associated protein of telencephalic dendrites and of podocytes in the kidney glomerulus. Annals of Anatomy 180: 391-2. No abstract available.

Mundel P, Heid HW, Mundel TM, Kruger M, Reiser J & Kriz W (1997). Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytes. Journal of Cell Biology 139: 193-204.

Mundel P, Gilbert P & Kriz W (1991). Podocytes in glomerulus of rat kidney express a characteristic 44 KD protein. Journal of Histochemistry and Cytochemistry 39: 1047-56.