Synaptojanin 1
A phosphoinositide phosphatase
References SySy synaptojanin 1 antibodies
Uthaiah RC & Hudspeth AJ (2010). Molecular anatomy of the hair cell's ribbon synapse. Journal of Neuroscience 30: 12387-99. C-terminus; WBPark J, Kim Y, Lee S, Park JJ, Park ZY, Sun W, Kim H & Chang S (2010). SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane. Journal of Cell Science 123(Pt10): 1742-50. C-terminus; WB
Shin N, Lee S, Ahn N, Kim SA, Ahn SG, YongPark Z & Chang S (2007). Sorting nexin 9 interacts with dynamin 1 and N-WASP and coordinates synaptic vesicle endocytosis. Journal of Biological Chemistry 282: 28939-50. C-terminus; WB
Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmüller H, Heuser J, Wieland F & Jahn R (2006). Molecular anatomy of a trafficking organelle. Cell 127: 831-46. WB in supplement
tom Dieck S, Altrock WD, Kessels MM, Qualmann B, Regus H, Brauner D, Fejtova A, Bracko O, Gundelfinger ED & Brandstatter JH (2005). Molecular dissection of the photoreceptor ribbon synapse: physical interaction of Bassoon and RIBEYE is essential for the assembly of the ribbon complex. Journal of Cell Biology 168: 825-36. WB
General references synaptojanin 1
Lee SY, Wenk MR, Kim Y, Nairn AC & De Camilli P (2004). Regulation of synaptojanin 1 by cyclin-dependent kinase 5 at synapses. Proceedings of the National Acadamy of Sciences USA 101: 546-51.Schuske KR, Richmond JE, Matthies DS, Davis WS, Runz S, Rube DA, van der Bliek AM & Jorgensen EM (2003). Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron 40: 749-62.
Verstreken P, Koh TW, Schulze KL, Zhai RG, Hiesinger PR, Zhou Y, Mehta SQ, Cao Y, Roos J & Bellen HJ (2003). Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron 40: 733-48.
Song W & Zinsmaier KE (2003). Endophilin and synaptojanin hook up to promote synaptic vesicle endocytosis. Neuron 40: 665-7. Review
Luthi A, Di Paolo G, Cremona O, Daniell L, De Camilli P & McCormick DA (2001). Synaptojanin 1 contributes to maintaining the stability of GABAergic transmission in primary cultures of cortical neurons. Journal of Neuroscience 21: 9101-11.
Harris TW, Hartwieg E, Horvitz HR & Jorgensen EM (2000). Mutations in synaptojanin disrupt synaptic vesicle recycling. Journal of Cell Biology 150: 589-600.
Haffner C, Di Paolo G, Rosenthal JA & de Camilli P (2000). Direct interaction of the 170 kDa isoform of synaptojanin 1 with clathrin and with the clathrin adaptor AP-2. Current Biology 10: 471-4.
Woscholski R, Finan PM, Radley E, Totty NF, Sterling AE, Hsuan JJ, Waterfield MD & Parker PJ (1997). Synaptojanin is the major constitutively active phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase in rodent brain. Journal of Biological Chemistry 272: 9625-8.
de Heuvel E, Bell AW, Ramjaun AR, Wong K, Sossin WS & McPherson PS (1997). Identification of the major synaptojanin-binding proteins in brain. Journal of Biological Chemistry 272: 8710-6.
Ramjaun AR & McPherson PS (1996). Tissue-specific alternative splicing generates two synaptojanin isoforms with differential membrane binding properties. Journal of Biological Chemistry 271: 24856-61.
