Rab 5
GTP-binding protein involved in endocytosis
References SySy rab 5 antibodies
Perlini LE, Botti F, Fornasiero EF, Giannandrea M, Bonanomi D, Amendola M, Naldini L, Benfenati F & Valtorta F (2011). Effects of phosphorylation and neuronal activity on the control of synapse formation by synapsin I. Journal of Cell Science 124 (Pt 21): 3643-53.
rabbit antiserum; WB
Pavlos NJ, Grønborg M, Riedel D, Chua JJ, Boyken J, Kloepper TH, Urlaub H, Rizzoli SO & Jahn R (2010). Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. Journal of Neuroscience 30: 13441-53.
clone 621.3; WB, ICC in supplement
Abe N, Almenar-Queralt A, Lillo C, Shen Z, Lozach J, Briggs SP, Williams DS, Goldstein LS & Cavalli V (2009). Sunday Driver interacts with two distinct classes of axonal organelles. Journal of Biological Chemistry 284: 34628-39
Clone 621.3; IP
Sitaram A, Piccirillo R, Palmisano I, Harper DC, Dell'Angelica EC, Schiaffino MV & Marks MS (2009). Localization to mature melanosomes by virtue of cytoplasmic dileucine motifs is required for human OCA2 function. Molecular Biology of the Cell 20: 1464-77.
MAB; WB
Olsen O, Moore KA, Fukata M, Kazuta T, Trinidad JC, Kauer FW, Streuli M, Misawa H, Burlingame AL, Nicoll RA & Bredt DS (2005). Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. Journal of Cell Biology 170: 1127-34.
MAB; WB
Schluter OM, Khvotchev M, Jahn R & Sudhof TC (2002). Localization versus function of Rab3 proteins. Evidence for a common regulatory role in controlling fusion. Journal of Biological Chemistry 277: 40919-29.
Clone 621.3; immunoisolation of vesicles
Chamberlain LH, Burgoyne RD & Gould GW (2001). SNARE proteins are highly enriched in lipid rafts in PC12 cells: Implications for the spatial control of exocytosis. Proceedings of the National Academy of Sciences USA 99: 5619-24.
MAB; WB
Antonin W, Holroyd C, Tikkanen R, Honing S & Jahn R (2000). The R-SNARE endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes. Molecular Biology of the Cell 11: 3289-98.
Clone 621.3; WB
Fischer von Mollard G, Stahl B, Walch-Solimena C, Takei K, Daniels L, Khoklatchev A, De Camilli P, Südhof TC & Jahn R (1994). Localization of Rab5 to synaptic vesicles identifies endosomal intermediate in synaptic vesicle recycling pathway. European Journal of Cell Biology 65: 319-26.
General references rab 5
Somsel Rodman J & Wandinger-Ness A (2000). Rab GTPases coordinate endocytosis. Journal of Cell Science 113, Pt 2: 183-92.
Ikin AF, Annaert WG, Takei K, De Camilli P, Jahn R, Greengard P & Buxbaum JD (1996). Amyloid protein precursor is localized in nerve terminal preparations to Rab5-containing vesicular organelles distinct from those implicated in the synaptic vesicle pathway. Journal of Biological Chemistry 271: 31783-6.