Profilins

Regulators of the microfilament network

References SySy profilin antibodies

Giesemann T, Schwarz G, Nawrotzki R, Berhorster K, Rothkegel M, Schluter K, Schrader N, Schindelin H, Mendel RR, Kirsch J & Jockusch BM (2003). Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system. Journal of Neuroscience 23: 8330-9. Clone 2H11; ICC

Janke J, Schluter K, Jandrig B, Theile M, Kolble K, Arnold W, Grinstein E, Schwartz A, Estevez-Schwarz L, Schlag PM, Jockusch BM & Scherneck S (2000). Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1. Journal of Experimental Medicine 191: 1675-86. Clone 2H11; WB, ICC

Wittenmayer N, Rothkegel M, Jockusch BM & Schluter K. (2000). Functional characterization of green fluorescent protein-profilin fusion proteins. European Journal of Biochemistry 267: 5247-56.

Giesemann T, Rathke-Hartlieb S, Rothkegel M, Bartsch JW, Buchmeier S, Jockusch BM & Jockusch H (1999). A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems. Journal of Biological Chemistry 274: 37908-14. Clone 2H11; ICC

Schluter K, Schleicher M & Jockusch BM (1998). Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin I. Journal of Cell Science 111: 3261-73. Description of Clone 2H11

Wiedemann P, Giehl K, Almo SC, Fedorov AA, Girvin M, Steinberger P, Rudiger M, Ortner M, Sippl M, Dolecek C, Kraft D, Jockusch B & Valenta R (1996). Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody. Journal of Biological Chemistry 271: 29915-21. Description of Clone 4A6

General references profilin

Neuhoff H, Sassoe-Pognetto M, Panzanelli P, Maas C, Witke W & Kneussel M (2005). The actin-binding protein profilin I is localized at synaptic sites in an activity-regulated manner. European Journal of Neuroscience21: 15-25.

Wittenmayer N, Jandrig B, Rothkegel M, Schluter K, Arnold W, Haensch W, Scherneck S & Jockusch BM (2004). Tumor suppressor activity of profilin requires a functional actin binding site. Molecular Biology of the Cell 15: 1600-9.

Rudiger M, Jockusch BM & Rothkegel M (1997). Epitope tag-antibody combination useful for the detection of protein expression in prokaryotic and eukaryotic cells. Biotechniques 23: 96-7. No abstract available