Piccolo (Aczonin)
A large multi-domain protein of the presynaptic active zone
References SySy piccolo antibodies
Ruiz R, Cano R, Casañas JJ, Gaffield MA, Betz WJ & Tabares L (2011). Active zones and the readily releasable pool of synaptic vesicles at the neuromuscular junction of the mouse. Journal of Neuroscience 31: 2000-8. rabbit antibody; IHCChen J, Billings SE & Nishimune H (2011). Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones. Journal of Neuroscience 31: 512-25. rabbit antibody; IHC
Dani A, Huang B, Bergan J, Dulac C & Zhuang X (2010). Superresolution imaging of chemical synapses in the brain. Neuron 68: 843-56. rabbit antibody; IHC
Varela-Nallar L, Alfaro IE, Serrano FG, Parodi J & Inestrosa NC (2010). Wingless-type family member 5A (Wnt-5a) stimulates synaptic differentiation and function of glutamatergic synapses. Proceedings of the National Academy of Sciences USA 107: 21164-9. rabbit antibody; ICC
Scott DA, Tabarean I, Tang Y, Cartier A, Masliah E & Roy S (2010). A pathologic cascade leading to synaptic dysfunction in alpha-synuclein-induced neurodegeneration. Journal of Neuroscience 30: 8083-95. rabbit antibody; ICC
Ribic A, Zhang M, Schlumbohm C, Mätz-Rensing K, Uchanska-Ziegler B, Flügge G, Zhang W, Walter L & Fuchs E (2010). Neuronal MHC Class I Molecules are Involved in Excitatory Synaptic Transmission at the Hippocampal Mossy Fiber Synapses of Marmoset Monkeys. Cellular and Molecular Neurobiology 30: 827-39. rabbit antiserum; IHC
Szodorai A, Kuan YH, Hunzelmann S, Engel U, Sakane A, Sasaki T, Takai Y, Kirsch J, Müller U, Beyreuther K, Brady S, Morfini G & Kins S (2009). APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. Journal of Neuroscience 29: 14534-44. rabbit antiserum;WB
Wahlin KJ, Moreira EF, Huang H, Yu N & Adler R (2008). Molecular dynamics of photoreceptor synapse formation in the developing chick retina. Journal of Comparative Neurology 506: 822-37. rabbit antiserum; WB, IHC
Khanna R, Zougman A & Stanley EF (2007). A proteomic screen for presynaptic terminal N-type calcium channel (CaV2.2) binding partners. Journal of Biochemistry & Molecular Biology 40: 302-14.
Tokoro T, Higa S, Deguchi-Tawarada M, Inoue E, Kitajima I & Ohtsuka T (2007). Localization of the active zone proteins CAST, ELKS, and Piccolo at neuromuscular junctions. Neuroreport 18: 313-6. rabbit antiserum; ICC
Dresbach T, Torres V, Wittenmayer N, Altrock WD, Zamorano P, Zuschratter W, Nawrotzki R, Ziv NE, Garner CC & Gundelfinger ED (2006). Assembly of active zone precursor vesicles: obligatory trafficking of presynaptic cytomatrix proteins Bassoon and Piccolo via a trans-Golgi compartment. Journal of Biological Chemistry 281: 6038-47. rabbit antiserum; ICC
Juranek J, Mukherjee K, Rickmann M, Martens H, Calka J, Sudhof TC & Jahn R (2006). Differential expression of active zone proteins in neuromuscular junctions suggests functional diversification. European Journal of Neuroscience 24: 3043-52. rabbit antiserum; ICC
Haeberle H, Fujiwara M, Chuang J, Medina MM, Panditrao MV, Bechstedt S, Howard J & Lumpkin EA (2004). Molecular profiling reveals synaptic release machinery in Merkel cells. Proceedings of the National Academy of Sciences USA 101:14503-8. rabbit antiserum; ICC
General references piccolo
Shapira M, Zhai RG, Dresbach T, Bresler T, Torres VI, Gundelfinger ED, Ziv NE & Garner CC (2003). Unitary assembly of presynaptic active zones from Piccolo-Bassoon transport vesicles. Neuron 38: 237-52.Fenster SD, Kessels MM, Qualmann B, Chung WJ, Nash J, Gundelfinger ED & Garner CC (2003). Interactions between Piccolo and the actin/dynamin-binding protein Abp1 link vesicle endocytosis to presynaptic active zones. Journal of Biological Chemistry 278: 20268-77.
Fenster SD & Garner CC (2002). Gene structure and genetic localization of the PCLO gene encoding the presynaptic active zone protein Piccolo. International Journal of Developmental Neuroscience 20: 161-71.
Dick O, Hack I, Altrock WD, Garner CC, Gundelfinger ED & Brandstatter JH (2001). Localization of the presynaptic cytomatrix protein Piccolo at ribbon and conventional synapses in the rat retina: comparison with Bassoon. Journal of Comparative Neurology 439: 224-34.
Gerber SH, Garcia J, Rizo J & Sudhof TC (2001). An unusual C(2)-domain in the active-zone protein piccolo: implications for Ca(2+) regulation of neurotransmitter release. EMBO Journal 20: 1605-19.
Fenster SD, Chung WJ, Zhai R, Cases-Langhoff C, Voss B, Garner AM, Kaempf U, Kindler S, Gundelfinger ED & Garner CC (2000). Piccolo, a presynaptic zinc finger protein structurally related to bassoon. Neuron 25: 203-14.
Cases-Langhoff C, Voss B, Garner AM, Appeltauer U, Takei K, Kindler S, Veh RW, De Camilli P, Gundelfinger ED & Garner CC (1996). Piccolo, a novel 420 kDa protein associated with the presynaptic cytomatrix. European Journal of Cell Biology 69: 214-23.
