Neuroligin 2
A postsynaptic cell adhesion molecule localized to postsynaptic densities of inhibitory synapses
References SySy neuroligin antibodies
Sun C, Cheng MC, Qin R, Liao DL, Chen TT, Koong FJ, Chen G & Chen CH (2011). Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia. Human Molecular Genetics 20: 3042-51.
rabbit antibody; WB
Varley ZK, Pizzarelli R, Antonelli R, Stancheva SH, Kneussel M, Cherubini E & Zacchi P (2011). Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures. Journal of Biological Chemistry 286: 20942-51.
affinity purified rabbit antibody; WB, ICC
Briatore F, Patrizi A, Viltono L, Sassoè-Pognetto M & Wulff P (2010).Quantitative organization of GABAergic synapses in the molecular layer of the mouse cerebellar cortex. PLoSOne 5(8):e12119.
affinity purified rabbit antibody; IHC
De Jaco A, Comoletti D, Kovarik Z, Gaietta G, Radic Z, Lockridge O, Ellisman MH & Taylor P (2006).A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family. Journal of Biological Chemistry 281: 9667-76.
Clone 4F9; WB
Chih B, Engelman H & Scheiffele P (2005). Control of excitatory and inhibitory synapse formation by neuroligins. Science 307: 1324-8.
Erratum: Science 308: 1413. Clone 4F9; WB in supplement
Prange O, Wong TP, Gerrow K, Wang YT & El-Husseini A (2004). A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin. Proceedings of the National Academy of Sciences USA 101: 13915-20.
Bolliger MF, Frei K, Winterhalter KH & Gloor SM (2001). Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression. Biochemical Journal 356: 581-8.
General references neuroligin
Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR & Sudhof TC (2007). Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron 54: 919-31.
Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P & Sudhof TC (2005). Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. Journal of Biological Chemistry 280: 22365-74.
Varoqueaux F, Jamain S & Brose N (2004). Neuroligin 2 is exclusively localized to inhibitory synapses. European Journal of Cell Biology 83: 449-56.
Dresbach T, Neeb A, Meyer G, Gundelfinger ED & Brose N (2004). Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding. Molecular and Cellular Neurosciences 27: 227-35.
Song J, Ichtchenko K, Südhof TC & Brose N (1999). Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proceedings of the National Academy of Sciences USA 96: 1100-5.
Missler M, Fernandez-Chacon R & Sudhof TC (1998). The making of neurexins. Journal of Neurochemistry 71: 1339-47.
Review
Ichtchenko K, Nguyen T & Südhof TC (1996). Structures, alternative splicing, and neurexin binding of multiple neuroligins. Journal of Biological Chemistry 271: 2676-82.
Ichtchenko K, Hata Y, Nguyen Y, Ullrich B, Moomaw C & Südhof TC (1995). Neuroligin 1: A splice site specific ligand for beta neurexins. Cell 81: 435-43.
Südhof TC (1995). The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375: 645-53.
Review