Neuroligins

Postsynaptic cell adhesion molecules localized to postsynaptic densities of excitatory synapses

References SySy neuroligin antibodies

Gerrow K, Romorini S, Nabi SM, Colicos MA, Sala C & El-Husseini A (2006). A preformed complex of postsynaptic proteins is involved in excitatory synapse development. Neuron 49: 547-62. Clone 4C12

Graf ER, Kang Y, Hauner AM & Craig AM (2006). Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. Journal of Neuroscience 26: 4256-65.

De Jaco A, Comoletti D, Kovarik Z, Gaietta G, Radic Z, Lockridge O, Ellisman MH & Taylor P (2006).A mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein family. Journal of Biological Chemistry 281: 9667-76. Clone 4F9; WB

Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P & Sudhof TC (2005). Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. Journal of Biological Chemistry 280: 22365-74. Clone 4C12; WB, ICC

Chih B, Engelman H & Scheiffele P (2005). Control of excitatory and inhibitory synapse formation by neuroligins. Science 307: 1324-8. Erratum: Science 308: 1413. Clone 4F9; WB in supplement

Prange O, Wong TP, Gerrow K, Wang YT & El-Husseini A (2004). A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin. Proceedings of the National Academy of Sciences USA 101: 13915-20.

Comoletti D, Flynn R, Jennings LL, Chubykin A, Matsumura T, Hasegawa H, Sudhof TC & Taylor P (2003). Characterization of the interaction of a recombinant soluble neuroligin-1 with neurexin-1beta. Journal of Biological Chemistry 278: 50497-505. Clone 4C12

Bolliger MF, Frei K, Winterhalter KH & Gloor SM (2001). Identification of a novel neuroligin in humans which binds to PSD-95 and has a widespread expression. Biochemical Journal 356: 581-8.

General references neuroligin

Chubykin AA, Atasoy D, Etherton MR, Brose N, Kavalali ET, Gibson JR & Sudhof TC (2007). Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron 54: 919-31.

Chubykin AA, Liu X, Comoletti D, Tsigelny I, Taylor P & Sudhof TC (2005). Dissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autism. Journal of Biological Chemistry 280: 22365-74.

Varoqueaux F, Jamain S & Brose N (2004). Neuroligin 2 is exclusively localized to inhibitory synapses. European Journal of Cell Biology 83: 449-56.

Dresbach T, Neeb A, Meyer G, Gundelfinger ED & Brose N (2004). Synaptic targeting of neuroligin is independent of neurexin and SAP90/PSD95 binding. Molecular and Cellular Neurosciences 27: 227-35.

Song J, Ichtchenko K, Südhof TC & Brose N (1999). Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses. Proceedings of the National Academy of Sciences USA 96: 1100-5.

Missler M, Fernandez-Chacon R & Sudhof TC (1998). The making of neurexins. Journal of Neurochemistry 71: 1339-47. Review

Ichtchenko K, Nguyen T & Südhof TC (1996). Structures, alternative splicing, and neurexin binding of multiple neuroligins. Journal of Biological Chemistry 271: 2676-82.

Ichtchenko K, Hata Y, Nguyen Y, Ullrich B, Moomaw C & Südhof TC (1995). Neuroligin 1: A splice site specific ligand for beta neurexins. Cell 81: 435-43.

Südhof TC (1995). The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 375: 645-53. Review