Neurobeachin (NBEA)

A protein kinase A-anchoring protein

General Information

Neurobeachin, also referred to as NBEA, is a large ~330 kDa brain-specific protein that belongs to the BEACH (beige and Chediak-Higashi) family. The protein has been shown to locate to tubulovesicular neuronal endomembranes near the trans-Golgi synapses, but also throughout the cell. Neurobeachin binds to protein kinase A and after adding GTPγS concentrates at Golgi-near membranes.