MLC-2A

A myosin specific for the atrium of the mammalian heart

References SySy MLC-2A antibodies

Zhang J, Wilson GF, Soerens AG, Koonce CH, Yu J, Palecek SP, Thomson JA & Kamp TJ (2009). Functional cardiomyocytes derived from human induced pluripotent stem cells. Circulation Research 104: e30-41. ICC

Rust W, Balakrishnan T & Zweigerdt R (2009). Cardiomyocyte enrichment from human embryonic stem cell cultures by selection of ALCAM surface expression. Regenerative Medicine 4: 225-37. ICC

Smits AM, van Laake LW, den Ouden K, Schreurs C, Szuhai K, van Echteld CJ, Mummery CL, Doevendans PA & Goumans MJ (2009). Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. Cardiovascular Research 83: 527-35. IHC

Xu XQ, Zweigerdt R, Soo SY, Ngoh ZX, Tham SC, Wang ST, Graichen R, Davidson B, Colman A & Sun W (2008). Highly enriched cardiomyocytes from human embryonic stem cells. Cytotherapy 10: 376-89. ICC, IHC

Phillips BW, Horne R, Lay TS, Rust WL, Teck TT & Crook JM (2008). Attachment and growth of human embryonic stem cells on microcarriers. Journal of Biotechnology 138: 24-32. IHC

Phillips BW, Lim RY, Tan TT, Rust WL & Crook JM (2008). Efficient expansion of clinical-grade human fibroblasts on microcarriers: cells suitable for ex vivo expansion of clinical-grade hESCs. Journal of Biotechnology 134: 79-87. IHC

van Laake LW, Passier R, Monshouwer-Kloots J, Verkleij AJ, Lips DJ, Freund C, den Ouden K, Ward-van Oostwaard D, Korving J, Tertoolen LG, van Echteld CJ, Doevendans PA & Mummery CL (2007). Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. Stem Cell Research 1: 9-24. IHC

Dai W, Field LJ, Rubart M, Reuter S, Hale SL, Zweigerdt R, Graichen RE, Kay GL, Jyrala AJ, Colman A, Davidson BP, Pera M & Kloner RA (2007). Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts. Journal of Molecular and Cellular Cardiology 43: 504-16. IHC

General references MLC-2A

Satin J, Kehat I, Caspi O, Huber I, Arbel G, Itzhaki I, Magyar J, Schroder EA, Perlman I & Gepstein L (2004). Mechanism of spontaneous excitability in human embryonic stem cell derived cardiomyocytes. Journal of Physiology 559 (Pt 2): 479-96.

Kehat I, Amit M, Gepstein A, Huber I, Itskovitz-Eldor J & Gepstein L (2003). Development of cardiomyocytes from human ES cells. Methods in Enzymology 365: 461-73. No abstract available

Muller M, Fleischmann BK, Selbert S, Ji GJ, Endl E, Middeler G, Muller OJ, Schlenke P, Frese S, Wobus AM, Hescheler J, Katus HA & Franz WM (2000). Selection of ventricular-like cardiomyocytes from ES cells in vitro. FASEB Journal 14: 2540-8.

Palermo J, Gulick J, Colbert M, Fewell J & Robbins J (1996). Transgenic Remodeling of the Contractile Apparatus in the Mammalian Heart. Circulation Research 78: 504-9.