Liprin-α (Syd 2)

A protein involved in the development of presynaptic active zones

References SySy Liprin-α3 antibodies

Sakamoto S, Ishizaki T, Okawa K, Watanabe S, Arakawa T, Watanabe N & Narumiya S (2012). Liprin-α controls stress fiber formation by binding to mDia and regulating its membrane localization. Journal of Cell Science 125(Pt 1): 108-20. antiserum 2; WB

Lazarevic V, Schöne C, Heine M, Gundelfinger ED & Fejtova A (2011). Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing. Journal of Neuroscience 31: 10189-200. antiserum 1; WB

General references liprin-α3

Hofmeyer K, Maurel-Zaffran C, Sink H & Treisman JE (2006). Liprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting. Proceedings of the National Academy of Sciences USA 103: 11595-600.

Ko J, Na M, Kim S, Lee JR & Kim E (2003). Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. Journal of Biological Chemistry 278: 42377-85.

Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M, Premont RT, Weinberg RJ & Kim E (2003). Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. Journal of Neuroscience 23: 1667-77.

Kim S, Ko J, Shin H, Lee JR, Lim C, Han JH, Altrock WD, Garner CC, Gundelfinger ED, Premont RT, Kaang BK & Kim E (2003). The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. Journal of Biological Chemistry 278: 6291-300.

Serra-Pages C, Medley QG, Tang M, Hart A & Streuli M (1998). Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. Journal of Biological Chemistry 273: 15611-20.