Voltage-gated potassium channel Kv 2

The major Kv component in brain and cortex.

General references Kv 2

Kihira Y, Hermanstyne TO & Misonou H (2010). Formation of heteromeric Kv2 channels in mammalian brain neurons. Journal of Biological Chemistry 285: 15048-55.

Hermanstyne TO, Kihira Y, Misono K, Deitchler A, Yanagawa Y & Misonou H (2010). Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice. Journal of Comparative Neurology 518: 4298-310.

Wray D (2009). Intracellular regions of potassium channels: Kv2.1 and heag. European Biophysics Journal 38: 285-92. Review

Mulholland PJ, Carpenter-Hyland EP, Hearing MC, Becker HC, Woodward JJ & Chandler LJ (2008). Glutamate transporters regulate extrasynaptic NMDA receptor modulation of Kv2.1 potassium channels. Journal of Neuroscience 28: 8801-9.

Wolf-Goldberg T, Michaelevski I, Sheu L, Gaisano HY, Chikvashvili D & Lotan I (2006). Target soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) differently regulate activation and inactivation gating of Kv2.2 and Kv2.1: Implications on pancreatic islet cell Kv channels. Molecular Pharmacology 70: 818-28.

Kobrinsky E, Stevens L, Kazmi Y, Wray D & Soldatov NM (2006). Molecular rearrangements of the Kv2.1 potassium channel termini associated with voltage gating. Journal of Biological Chemistry 281: 19233-40.

O'Connell KM, Rolig AS, Whitesell JD & Tamkun MM (2006). Kv2.1 potassium channels are retained within dynamic cell surface microdomains that are defined by a perimeter fence. Journal of Neuroscience 26: 9609-18.

Park KS, Mohapatra DP, Misonou H & Trimmer JS (2006). Graded regulation of the Kv2.1 potassium channel by variable phosphorylation. Science USA 313: 976-9.

Lim ST, Antonucci DE, Scannevin RH & Trimmer JS (2000). A novel targeting signal for proximal clustering of the Kv2.1 K+ channel in hippocampal neurons. Neuron 25: 385-97.

Murakoshi H, Shi G, Scannevin RH & Trimmer JS (1997). Phosphorylation of the Kv2.1 K+ channel alters voltage-dependent activation. Molecular Pharmacology 52: 821-8.

Trimmer JS (1993). Expression of Kv2.1 delayed rectifier K+ channel isoforms in the developing rat brain. FEBS Letters 324: 205-10.

Hwang PM, Cunningham AM, Peng YW & Snyder SH (1993). CDRK and DRK1 K+ channels have contrasting localizations in sensory systems. Neuroscience 55: 613-20.

Ikeda SR, Soler F, Zühlke RD, Joho RH & Lewis DL (1992). Heterologous expression of the human potassium channel Kv2.1 in clonal mammalian cells by direct cytoplasmic microinjection of cRNA. Pflügers Archiv 422: 201-3.