Inositol 1, 4, 5 - trisphophate receptor (InsP3)

Triggers release of Ca²⁺ from intracellular stores

References SySy InsP3 receptor antibodies

Morciano M, Beckhaus T, Karas M, Zimmermann H & Volknandt W (2009). The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels. Journal of Neurochemistry 108: 662-75. WB

General references InsP3 receptor

Taylor CW, Genazzani AA & Morris SA (1999). Expression of inositol trisphosphate receptors. Cell Calcium 26: 237-51. Review, no abstract available

Dawson AP (1997). Calcium signalling: how do IP3 receptors work? Current Biology 7: R544-7. Review

Südhof TC, Newton CL, Archer BT 3rd, Ushkaryov YA & Mignery GA (1991). Structure of a novel InsP3 receptor. EMBO Journal 10: 3199-206.

Mignery GA, Südhof TC, Takei K & De Camilli P (1989). Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor. Nature 342: 192-5.

Furuichi T, Yoshikawa S, Miyawaki A, Wada K, Maeda N & Mikoshiba K (1989). Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400. Nature 342: 32-8.