Homer 1 (VesL 1, Syn 47)

A post synaptic density (PSD) protein involved in the targeting of glutamate receptors

References SySy homer 1 antibodies

Lazarevic V, Schöne C, Heine M, Gundelfinger ED & Fejtova A (2011). Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing. Journal of Neuroscience 31: 10189-200. homer 1 rabbit antibody; WB, ICC

Hua Y, Sinha R, Thiel CS, Schmidt R, Hüve J, Martens H, Hell SW, Egner A & Klingauf J (2011). A readily retrievable pool of synaptic vesicles. Nature Neuroscience 14: 833-9. homer 1 rabbit antibody; ICC

Ökvist A, Fagergren P, Whittard J, Garcia-Osta A, Drakenberg K, Horvath MC, Schmidt CJ, Keller E, Bannon MJ & Hurd YL (2011). Dysregulated postsynaptic density and endocytic zone in the amygdala of human heroin and cocaine abusers. Biological Psychiatry 69: 245-52. homer 1 rabbit antibody; WB

Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED & Boeckers TM (2011). Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO Journal 30: 569-81. homer 1 rabbit antibody; ICC

Dani A, Huang B, Bergan J, Dulac C & Zhuang X (2010). Superresolution imaging of chemical synapses in the brain. Neuron 68: 843-56. homer 1 rabbit antibody; IHC

Glyvuk N, Tsytsyura Y, Geumann C, D'Hooge R, Hüve J, Kratzke M, Baltes J, Boening D, Klingauf J & Schu P (2010). AP-1/σ1B-adaptin mediates endosomal synaptic vesicle recycling, learning and memory. EMBO Journal 29: 1318-30. homer 1 rabbit antibody; ICC

Tronson NC, Guzman YF, Guedea AL, Huh KH, Gao C, Schwarz MK & Radulovic J (2010). Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear. Biological Psychiatry 68: 1007-15. homer 1 rabbit antibody; WB, IHC

Soria Van Hoeve JS & Borst JG (2010). Delayed appearance of the scaffolding proteins PSD-95 and Homer-1 at the developing rat calyx of held synapse. Journal of Comparative Neurology 518: 4581-90. homer 1 rabbit antibody; IHC

Smalla KH, Sahin J, Putzke J, Tischmeyer W, Gundelfinger ED & Kreutz MR (2009). Altered postsynaptic-density-levels of caldendrin in the para-chloroamphetamine-induced serotonin syndrome but not in the rat ketamine model of psychosis. Neurochemical Research 34: 1405-9. homer 1 rabbit antibody; WB

Roselli F, Hutzler P, Wegerich Y, Livrea P & Almeida OF (2009). Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways. PloS one 4(6): e6011. homer 1 rabbit antibody; WB

McBride TJ, Rodriguez-Contreras A, Trinh A, Bailey R & Debello WM (2008). Learning drives differential clustering of axodendritic contacts in the barn owl auditory system. Journal of Neuroscience 28: 6960-73. homer 1 rabbit antibody; IHC

General references homer 1

Kammermeier PJ (2006). Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins. BMC Neuroscience 7: 1.

Yamamoto K, Sakagami Y, Sugiura S, Inokuchi K, Shimohama S, Kato N (2005). Homer 1a enhances spike-induced calcium influx via L-type calcium channels in neocortex pyramidal cells. European Journal of Neuroscience 22: 1338-48.

Shiraishi Y, Mizutani A, Yuasa S, Mikoshiba K & Furuichi T (2004). Differential expression of Homer family proteins in the developing mouse brain. Journal of Comparative Neurology 473: 582-99.

Saito H, Kimura M, Inanobe A, Ohe T & Kurachi Y (2002). An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells. Biochemical and Biophysical Research Communications 296: 523-9.

Thomas U (2002). Modulation of synaptic signalling complexes by Homer proteins. Journal of Neurochemistry 81: 407-13. Review

Ango F, Robbe D, Tu JC, Xiao B, Worley PF, Pin JP, Bockaert J & Fagni L (2002). Homer-dependent cell surface expression of metabotropic glutamate receptor type 5 in neurons. Molecular & Cellular Neurosciences 20: 323-9.

Sala C, Piech V, Wilson NR, Passafaro M, Liu G & Sheng M (2001). Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31: 115-30.

Soloviev MM, Ciruela F, Chan WY & McIlhinney RA (2000). Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing. Journal of Molecular Biology 295: 1185-200.

Ciruela F, Soloviev MM, Chan WY & McIlhinney RA (2000). Homer-1c/Vesl-1L modulates the cell surface targeting of metabotropic glutamate receptor type 1alpha: evidence for an anchoring function. Molecular & Cellular Neurosciences 15: 36-50.

Xiao B, Tu JC & Worley PF (2000). Homer: a link between neural activity and glutamate receptor function. Current Opinion in Neurobiology 10): 370-4. Review

Tu JC, Xiao B, Naisbitt S, Yuan JP, Petralia RS, Brakeman P, Doan A, Aakalu VK, Lanahan AA, Sheng M & Worley PF (1999). Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 23: 583-92.

Brakeman PR, Lanahan AA, O'Brien R, Roche K, Barnes CA, Huganir RL & Worley PF (1997). Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386: 284-8.