GRIP

A post-synaptic multi-PDZ domain protein

References SySy GRIP antibodies

Van Damme P, Bogaert E, Dewil M, Hersmus N, Kiraly D, Scheveneels W, Bockx I, Braeken D, Verpoorten N, Verhoeven K, Timmerman V, Herijgers P, Callewaert G, Carmeliet P, Van Den Bosch L & Robberecht W (2007). Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Proceedings of the National Academy of Sciences USA 104: 14825-30. WB in supplement

General references GRIP

Stegmuller J, Werner H, Nave KA & Trotter J (2003). The proteoglycan NG2 is complexed with alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the PDZ glutamate receptor interaction protein (GRIP) in glial progenitor cells. Implications for glial-neuronal signaling. Journal of Biological Chemistry 278: 3590-8.

Hirbec H, Perestenko O, Nishimune A, Meyer G, Nakanishi S, Henley JM & Dev KK (2002). The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. Journal of Biological Chemistry 277: 15221-4.

Yu G, Zerucha T, Ekker M & Rubenstein JL (2001). Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins. Brain Research. Developmental Brain Research 130: 217-30.

Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH & Klein R (1999). EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron 22: 511-24.

Dong H, O'Brien RJ, Fung ET, Lanahan AA, Worley PF & Huganir RL (1997). GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 386: 279-84.