GLUT 4
A glucose transporter involved in insulin stimulated glucose uptake
References SySy GLUT 4 antibodies
Boyle JG, Logan PJ, Jones GC, Small M, Sattar N, Connell JM, Cleland SJ & Salt IP (2011). AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study. Diabetologia 54: 1799-809.
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General references GLUT 4
Fukuda N, Emoto M, Nakamori Y, Taguchi A, Miyamoto S, Uraki S, Oka Y & Tanizawa Y (2009). DOC2B: a novel syntaxin-4 binding protein mediating insulin-regulated GLUT4 vesicle fusion in adipocytes. Diabetes 58: 377-84.
Li Y, Wang P, Xu J, Gorelick F, Yamazaki H, Andrews N & Desir GV (2007). Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII. Biochemical and Biophysical Research Communications 362: 658-64.
Foster LJ & Klip A (2000). Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells. American Journal of Physiology. Cell Physiology 279: C877-90.
Review
Thurmond DC, Ceresa BP, Okada S, Elmendorf JS, Coker K & Pessin JE (1998). Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes. Journal of Biological Chemistry 273: 33876-83.
Haney PM, Slot JW, Piper RC, James DE & Mueckler M (1991). Intracellular targeting of the insulin-regulatable glucose transporter (GLUT4) is isoform specific and independent of cell type. Journal of Cell Biology 114: 689-99.