Gephyrin
A protein associated with inhibitory neurotransmitter receptors
References SySy gephyrin antibodies
Hoon M, Soykan T, Falkenburger B, Hammer M, Patrizi A, Schmidt KF, Sassoè-Pognetto M, Löwel S, Moser T, Taschenberger H, Brose N & Varoqueaux F (2011). Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina. Proceedings of the National Academy of Sciences USA 108: 3053-8 Clone 3B11; WB, IHCHua Y, Sinha R, Thiel CS, Schmidt R, Hüve J, Martens H, Hell SW, Egner A & Klingauf J (2011). A readily retrievable pool of synaptic vesicles. Nature Neuroscience 14: 833-9. Clone mAb7a (hybridoma supernatant); ICC
Varley ZK, Pizzarelli R, Antonelli R, Stancheva SH, Kneussel M, Cherubini E & Zacchi P (2011). Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures. Journal of Biological Chemistry 286: 20942-51 Clone 3B11; WB
Förstera B, Belaidi AA, Jüttner R, Bernert C, Tsokos M, Lehmann TN, Horn P, Dehnicke C, Schwarz G & Meier JC (2010). Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain 133: 3778-94. Clone 3B11; WB, Clone mAb7a; ICC
Baer K, Waldvogel HJ, Faull RL & Rees MI (2009). Localization of glycine receptors in the human forebrain, brainstem, and cervical spinal cord: an immunohistochemical review. Frontiers in Molecular Neuroscience 2: #25. Clone 3B11; IHC
Smolinsky B, Eichler SA, Buchmeier S, Meier JC & Schwarz G (2008). Splice-specific functions of gephyrin in molybdenum cofactor biosynthesis. Journal of Biological Chemistry 283: 17370-9. Description of clone 3B11, WB
Baer K, Bürli T, Huh KH, Wiesner A, Erb-Vögtli S, Göckeritz-Dujmovic D, Moransard M, Nishimune A, Rees MI, Henley JM, Fritschy JM & Fuhrer C (2007). PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering. Molecular and Cellular Neurosciences 35: 339-55.
Schneider Gasser EM, Straub CJ, Panzanelli P, Weinmann O, Sassoè-Pognetto M & Fritschy JM (2006). Immunofluorescence in brain sections: simultaneous detection of presynaptic and postsynaptic proteins in identified neurons. Nature Protocols 1: 1887-97. Clone mAb7a; IHC protocol
Grady RM, Wozniak DF, Ohlemiller KK & Sanes JR (2006). Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. Journal of Neuroscience 26: 2841-51. Clone mAb7a; IHC
Aloy EM, Weinmann O, Pot C, Kasper H, Dodd DA, Rülicke T, Rossi F & Schwab ME (2006). Synaptic destabilization by neuronal Nogo-A. Brain Cell Biology 35: 137-56. Clone mAb7a; IHC
Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe-Siefke C & Kneussel M (2006). Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. Journal of Cell Biology 172: 441-51. Clone mAb7a; ICC
Graf ER, Kang Y, Hauner AM & Craig AM (2006). Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. Journal of Neuroscience 26: 4256-65. Clone mAb7a; ICC
Kralic JE, Sidler C, Parpan F, Homanics GE, Morrow AL & Fritschy JM (2006). Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice. Journal of Comparative Neurology 495: 408-21. Clone mAb7a; IHC
Hartman KN, Pal SK, Burrone J & Murthy VN (2006). Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nature Neuroscience 9: 642-9. Clone mAb7a; ICC
Jacob TC, Bogdanov YD, Magnus C, Saliba RS, Kittler JT, Haydon PG & Moss SJ (2005). Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors. Journal of Neuroscience 25: 10469-78. Clone mAb7a; ICC
Meier J & Grantyn R (2004). A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses. Journal of Neuroscience 24: 1398-405. Clone mAb7a; ICC
Oleskevich S, Alvarez FJ & Walmsley B (1999). Glycinergic miniature synaptic currents and receptor cluster sizes differ between spinal cord interneurons. Journal of Neurophysiology 82: 312-9. Clone mAb7a; IHC
Pfeiffer F, Simler R, Grenningloh G & Betz H (1984). Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord. Proceedings of the National Academy of Sciences USA 81: 7224-7. Description of clone mAb7a
General references gephyrin
Hermann A, Kneussel M & Betz H (2001). Identification of multiple gephyrin variants in different organs of the adult rat. Biochemical & Biophysical Research Communications 282: 67-70.Kirsch J & Betz H (1993). Widespread expression of gephyrin, a putative glycine receptor-tubulin linker protein, in rat brain. Brain Research 621: 301-10.
Kirsch J, Malosio ML, Wolters I & Betz H (1993). Distribution of gephyrin transcripts in the adult and developing rat brain. European Journal of Neuroscience 5: 1109-17.
