Endophilin (SH3P4, SH3GL2)

An SH3 domain protein involved in clathrin mediated endocytosis

General references endophilin

Vinatier J, Herzog E, Plamont MA, Wojcik SM, Schmidt A, Brose N, Daviet L, El Mestikawy S & Giros B (2006). Interaction between the vesicular glutamate transporter type 1 and endophilin A1, a protein essential for endocytosis. Journal of Neurochemistry 97: 1111-25.

Schuske KR, Richmond JE, Matthies DS, Davis WS, Runz S, Rube DA, van der Bliek AM & Jorgensen EM (2003). Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin. Neuron 40: 749-62.

Verstreken P, Koh TW, Schulze KL, Zhai RG, Hiesinger PR, Zhou Y, Mehta SQ, Cao Y, Roos J & Bellen HJ (2003). Synaptojanin is recruited by endophilin to promote synaptic vesicle uncoating. Neuron 40: 733-48.

Song W & Zinsmaier KE (2003). Endophilin and synaptojanin hook up to promote synaptic vesicle endocytosis. Neuron 40: 665-7. Review

Chen Y, Deng L, Maeno-Hikichi Y, Lai M, Chang S, Chen G & Zhang JF (2003). Formation of an endophilin-Ca2+ channel complex is critical for clathrin-mediated synaptic vesicle endocytosis. Cell 115: 37-48.

Reutens AT & Begley CG (2002). Endophilin-1: a multifunctional protein. International Journal of Biochemistry & Cell Biology 34: 1173-7. Review

Verstreken P, Kjaerulff O, Lloyd TE, Atkinson R, Zhou Y, Meinertzhagen IA & Bellen HJ (2002). Endophilin mutations block clathrin-mediated endocytosis but not neurotransmitter release. Cell 109: 101-12.

Gad H, Ringstad N, Low P, Kjaerulff O, Gustafsson J, Wenk M, Di Paolo G, Nemoto Y, Crun J, Ellisman MH, De Camilli P, Shupliakov O & Brodin L (2000). Fission and uncoating of synaptic clathrin-coated vesicles are perturbed by disruption of interactions with the SH3 domain of endophilin. Neuron 27: 301-12.

Ringstad N, Gad H, Low P, Di Paolo G, Brodin L, Shupliakov O & De Camilli P (1999). Endophilin/SH3p4 is required for the transition from early to late stages in clathrin-mediated synaptic vesicle endocytosis. Neuron 24: 143-54.

Schmidt A, Wolde M, Thiele C, Fest W, Kratzin H, Podtelejnikov AV, Witke W, Huttner WB & Soling HD (1999). Endophilin I mediates synaptic vesicle formation by transfer of arachidonate to lysophosphatidic acid. Nature 401: 133-41.

Micheva KD, Kay BK & McPherson PS (1997). Synaptojanin forms two separate complexes in the nerve terminal. Interactions with endophilin and amphiphysin. Journal of Biological Chemistry 272: 27239-45.

Micheva KD, Ramjaun AR, Kay BK & McPherson PS (1997). SH3 domain-dependent interactions of endophilin with amphiphysin. FEBS Letters 414: 308-12. Erratum in FEBS Letters 419: 150