Endobrevin (VAMP8)

Endosomal fusion protein, member of the R-SNARE family

References SySy endobrevin antibodies

Offenhäuser C, Lei N, Roy S, Collins BM, Stow JL & Murray RZ (2011). Syntaxin 11 binds Vti1b and regulates late endosome to lysosome fusion in macrophages. Traffic 12: 762-73. WB

Kreda SM, Seminario-Vidal L, van Heusden CA, O'Neal W, Jones L, Boucher RC & Lazarowski ER (2010). Receptor-promoted exocytosis of airway epithelial mucin granules containing a spectrum of adenine nucleotides. Journal of Physiology Apr 26, [Epub ahead of print] ICC

Wang CC, Ng CP, Shi H, Liew HC, Guo K, Zeng Q & Hong W (2010). A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2. Molecular and Cellular Biology 30: 333-43 WB, IHC

Fletcher PL Jr, Fletcher MD, Weninger K, Anderson TE & Martin BM (2010). Vesicle-associated membrane protein (VAMP) cleavage by a new metalloprotease from the Brazilian scorpion Tityus serrulatus. Journal of Biological Chemistry 285: 7405-16. WB

Ho YH, Cai DT, Wang CC, Huang D & Wong SH (2008). Vesicle-associated membrane protein-8/endobrevin negatively regulates phagocytosis of bacteria in dendritic cells. Journal of Immunology 180: 3148-57. WB, ICC

Brunner Y, Couté Y, Iezzi M, Foti M, Fukuda M, Hochstrasser DF, Wollheim CB & Sanchez JC (2007). Proteomics analysis of insulin secretory granules. Molecular and Cellular Proteomics 6: 1007-17. ICC

Larance M, Ramm G, Stockli J, van Dam EM, Winata S, Wasinger V, Simpson F, Graham M, Junutula JR, Guilhaus M & James DE (2005). Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. Journal of Biological Chemistry 280: 37803-13. WB

Murray RZ, Wylie FG, Khromykh T, Hume DA & Stow JL (2005). Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha. Journal of Biological Chemistry 280: 10478-83. IP

Schraw TD, Rutledge TW, Crawford GL, Bernstein AM, Kalen AL, Pessin JE & Whiteheart SW (2003). Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood 102: 1716-22. WB

Antonin W, Holroyd C, Tikkanen R, Honing S & Jahn R (2000). The R-SNARE Endobrevin/VAMP-8 mediates homotypic fusion of early endosomes and late endosomes. Molecular Biology of the Cell 11: 3289-98. WB

Antonin W, Holroyd C, Fasshauer D, Pabst S, Fischer Von Mollard G & Jahn R (2000). A SNARE complex mediating fusion of late endosomes defines conserved properties of SNARE structure and function. EMBO Journal 19: 6453-64. WB

Fasshauer D, Antonin W, Margittai M, Pabst S, Jahn R (1999). Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties. Journal of Biological Chemistry 274: 15440-6. WB

General references endobrevin

Jahn R & Sudhof TC (1999). Membrane fusion and exocytosis. Annual Review in Biochemistry 68: 863-911. Review

Advani RJ, Bae HR, Bock JB, Chao DS, Doung YC, Prekeris R, Yoo JS & Scheller RH (1998). Seven novel mammalian SNARE proteins localize to distinct membrane compartments. Journal of Biological Chemistry 273: 10317-24.

Wong SH, Zhang T, Xu Y, Subramaniam VN, Griffiths G, Hong W (1998). Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome. Molecular Biology of the Cell 9: 1549-63.