CtBP 2

A transcriptional corepressor

General Information

CtBP 2 and its close relative CtBP 1 interact with various transcription factors through a PLDLSL motif enhancing transcriptional repression. With the exception of the first 20 amino acids CtBP 2 is identical to the B-domain of ribeye, a scaffolding protein of the ribbon synapse. Both proteins originate from the same gene.