Cortactin
A cortical actin binding protein
References SySy cortactin antibodies
Lai FP, Szczodrak M, Oelkers JM, Ladwein M, Acconcia F, Benesch S, Auinger S, Faix J, Small JV, Polo S, Stradal TE & Rottner K (2009). Cortactin Promotes Migration and PDGF-induced Actin Reorganization by Signaling to Rho-GTPases. Molecular Biology of the Cell 20: 3209-23. Clone 10C6; WB in supplement, clone 289H10; ICCGeneral references cortactin
Tehrani S, Tomasevic N, Weed S, Sakowicz R & Cooper JA (2007). Src phosphorylation of cortactin enhances actin assembly. Proceedings of the National Academy of Sciences USA 104: 11933-8.Sousa S, Cabanes D, Bougneres L, Lecuit M, Sansonetti P, Tran-Van-Nhieu G & Cossart P (2007). Src, cortactin and Arp2/3 complex are required for E-cadherin-mediated internalization of Listeria into cells. Cellular Microbiology 9: 2629-43.
Cosen-Binker LI & Kapus A (2006). Cortactin: the gray eminence of the cytoskeleton. Physiology (Bethesda) 21: 352-61. Review
Kim K, Hou P, Gorski JL & Cooper JA (2004). Effect of Fgd1 on cortactin in Arp2/3 complex-mediated actin assembly. Biochemistry 43: 2422-7.
Helwani FM, Kovacs EM, Paterson AD, Verma S, Ali RG, Fanning AS, Weed SA & Yap AS (2004). Cortactin is necessary for E-cadherin-mediated contact formation and actin reorganization. Journal of Cell Biology 164: 899-910.
Hering H & Sheng M (2003). Activity-dependent redistribution and essential role of cortactin in dendritic spine morphogenesis. Journal of Neuroscience 23: 11759-69.
Redecker P, Gundelfinger ED & Boeckers TM (2001). The cortactin-binding postsynaptic density protein proSAP1 in non-neuronal cells. Journal of Histochemistry and Cytochemistry 49: 639-48.
Boeckers TM, Kreutz MR, Winter C, Zuschratter W, Smalla KH, Sanmarti-Vila L, Wex H, Langnaese K, Bockmann J, Garner CC & Gundelfinger ED (2001). Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. Annals of Anatomy 183: 101. No abstract available
Olazabal IM & Machesky LM (2001). Abp1p and cortactin, new "hand-holds" for actin. Journal of Cell Biology 154: 679-82. Review
Kinnunen T, Kaksonen M, Saarinen J, Kalkkinen N, Peng HB & Rauvala H (1998). Cortactin-Src kinase signaling pathway is involved in N-syndecan-dependent neurite outgrowth. Journal of Biological Chemistry 273: 10702-8.
Peng HB, Xie H & Dai Z (1997). Association of cortactin with developing neuromuscular specializations. Journal of Neurocytology 26: 637-50.
Okamura H & Resh MD (1995). p80/85 cortactin associates with the Src SH2 domain and colocalizes with v-Src in transformed cells. Journal of Biological Chemistry 270: 26613-8.
Durieu-Trautmann O, Chaverot N, Cazaubon S, Strosberg AD & Couraud PO (1994). Intercellular adhesion molecule 1 activation induces tyrosine phosphorylation of the cytoskeleton-associated protein cortactin in brain microvessel endothelial cells. Journal of Biological Chemistry 269: 12536-40.
Wu H & Parsons JT (1993). Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex. Journal of Cell Biology 120: 1417-26.
