Clathrin light chain

Small clathrin coat subunits involved in endocytosis

General Information

Clathrin consists of heavy chains and light chains that co-assemble to triskelions. The light chains are differentially spliced, with neurons expressing a special variant that is not detectable elsewhere. The neuron-specific light chains are enriched in synaptic nerve terminals where they participate in synaptic vesicle endocytosis.