Calbindins

Vitamin D-dependent calcium binding proteins

General Information

Two isoforms (D28k and D29k) of the the vitamin D-dependent Ca-binding proteins called calbindins have been described so far. These proteins are expressed in cells that have to handle a high calcium influx such as brain, bone, teeth, inner ear and others. Calbindins are believed to regulate cellular activity by suppressing or buffering intracellur calcium.
Calbindin D28k is also referred to as CALB 1, D-28k, and CAB 27, calbindin D29k is also known as calretinin, calbindin 2, CALB 2, CAL 2, and CAB 29.