Arc
A cytoskeleton-associated protein involved in neuronal plasticity
References SySy Arc antibodies
Jourdi H, Hsu YT, Zhou M, Qin Q, Bi X & Baudry M (2009). Positive AMPA receptor modulation rapidly stimulates BDNF release and increases dendritic mRNA translation. Journal of Neuroscience 29: 8688-97. rabbit antibody; WBWiig KA, Whitlock JR, Epstein MH, Carpenter RL & Bear MF (2009). The levo enantiomer of amphetamine increases memory consolidation and gene expression in the hippocampus without producing locomotor stimulation. Neurobiology of Learning and Memory 92: 106-13. rabbit antibody; WB
Waung MW, Pfeiffer BE, Nosyreva ED, Ronesi JA & Huber KM (2008). Rapid translation of Arc/Arg3.1 selectively mediates mGluR-dependent LTD through persistent increases in AMPAR endocytosis rate. Neuron 59: 84-97. rabbit antibody; IP, ICC in supplement
Panford-Walsh R, Singer W, Ruttiger L, Hadjab S, Tan J, Geisler HS, Zimmermann U, Kopschall I, Rohbock K, Vieljans A, Oestreicher E & Knipper M (2008). Midazolam Reverses Salicylate Induced Changes in BDNF and Arg3.1 Expression: Implications for Tinnitus Perception and Auditory Plasticity. Molecular Pharmacology 74: 595-604. rabbit antibody; IHC
Thomsen MS, Mikkelsen JD, Timmermann DB, Peters D, Hay-Schmidt A, Martens H & Hansen HH (2008). The selective alpha(7) nicotinic acetylcholine receptor agonist A-582941 activates immediate early genes in limbic regions of the forebrain: Differential effects in the juvenile and adult rat. Neuroscience 154: 741-53. rabbit antibody; IHC
General references Arc
Larsen MH, Olesen M, Woldbye DP, Hay-Schmidt A, Hansen HH, Ronn LC & Mikkelsen JD (2005). Regulation of activity-regulated cytoskeleton protein (Arc) mRNA after acute and chronic electroconvulsive stimulation in the rat. Brain Research 1064: 161-5.McIntyre CK, Miyashita T, Setlow B, Marjon KD, Steward O, Guzowski JF & McGaugh JL (2005). Memory-influencing intra-basolateral amygdala drug infusions modulate expression of Arc protein in the hippocampus. Proceedings of the National Academy of Sciences U.S.A. 103: 10718-23.
Chawla MK, Guzowski JF, Ramirez-Amaya V, Lipa P, Hoffman KL, Marriott LK, Worley PF, McNaughton BL & Barnes CA (2005). Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience. Hippocampus 15: 579-86.
Vazdarjanova A, McNaughton BL, Barnes CA, Worley PF & Guzowski JF (2002). Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks. Journal of Neuroscience 22: 10067-71.
Guzowski JF, Lyford GL, Stevenson GD, Houston FP, McGaugh JL, Worley PF & Barnes CA (2000). Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. Journal of Neuroscience 20: 3993-4001.
Tan A, Moratalla R, Lyford GL, Worley P & Graybiel AM. (2000). The activity-regulated cytoskeletal-associated protein arc is expressed in different striosome-matrix patterns following exposure to amphetamine and cocaine. Journal of Neurochemistry 74: 2074-8.
Guzowski JF, McNaughton BL, Barnes CA & Worley PF (1999). Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nature Neuroscience 2: 1120-4.
Steward O, Wallace CS, Lyford GL & Worley PF (1998). Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21: 741-51.
Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, Copeland NG, Gilbert DJ, Jenkins NA, Lanahan AA & Worley PF (1995). Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14: 433-45.
