Amyloid precursor protein (APP)
Protein involved in Alzheimer's disease
References SySy APP antibodies
Groemer TW, Thiel CS, Holt M, Riedel D, Hua Y, Hüve J, Wilhelm BG & Klingauf J (2011). Amyloid Precursor Protein Is Trafficked and Secreted via Synaptic Vesicles. PLoS one 6(4): e18754. WB, ICC, EMChristensen DZ, Schneider-Axmann T, Lucassen PJ, Bayer TA & Wirths O (2010). Accumulation of intraneuronal Abeta correlates with ApoE4 genotype. Acta Neuropathologica 119: 555-66. IHC
Christensen DZ, Schneider-Axmann T, Lucassen PJ, Bayer TA & Wirths O (2010). Accumulation of intraneuronal Abeta correlates with ApoE4 genotype. Acta Neuropathologica 119: 555-66. IHC
Christensen DZ, Bayer TA & Wirths O (2009). Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Abeta peptides in mouse models of Alzheimer's disease. Brain Research 1301: 116-25. IHC
Shrivastava-Ranjan P, Faundez V, Fang G, Rees H, Lah JJ, Levey AI & Kahn RA (2008). Mint3/X11{gamma} Is an ADP-Ribosylation Factor-dependent Adaptor that Regulates the Traffic of the Alzheimer's Precursor Protein from the Trans-Golgi Network. Molecular Biology of the Cell 19: 51-64. WB
van Groen T, Puurunen K, Maki HM, Sivenius J & Jolkkonen J (2005). Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in rats. Stroke 36: 1551-6. IHC
General references APP
Storey E & Cappai R (1999). The amyloid precursor protein of Alzheimer's disease and the Abeta peptide. Neuropathology & Applied Neurobiology 25: 81-97. ReviewCruts M & Van Broeckhoven C (1998). Molecular genetics of Alzheimer's disease. Annals of Medicine 30: 560-5. Review
Beyreuther K, Multhaup G, Monning U, Sandbrink R, Beher D, Hesse L, Small DH & Masters CL (1996). Regulation of APP expression, biogenesis and metabolism by extracellular matrix and cytokines. Annals of the New York Academy of Sciences 777: 74-6. Review
Selkoe DJ, Yamazaki T, Citron M, Podlisny MB, Koo EH, Teplow DB & Haass C (1996). The role of APP processing and trafficking pathways in the formation of amyloid beta-protein. Annals of the New York Academy of Sciences 777: 57-64.
